Properties
| Name: | IGF-1 LR3 |
|---|---|
| Purity: | ~99% HPLC |
| Vial Contents: | Lyophilized Powder |
| CAS Number: | 946870-92-4 |
| Also Known As: | Long Arginine 3-IGF-1 |
| Molecular Weight: | 9117.5 g/mol |
| Molecular Formula: | C400H625N111O115S9 |
Product Details
Description:
IGF-1 LR3 (Long Arginine 3-IGF-1) is a synthetic, recombinant protein analogue of Insulin-like Growth Factor-1 (IGF-1). This analogue is structurally modified with an N-terminal extension of 13 amino acids and a substitution of an arginine for the glutamic acid at the third position. These modifications significantly reduce its binding affinity to IGF-binding proteins (IGFBPs).
In a research context, the reduced affinity for IGFBPs makes IGF-1 LR3 a potent tool for *in vitro* studies. It is used to investigate cellular growth, proliferation, and differentiation pathways by more effectively stimulating the IGF-1 receptor (IGF-1R). Researchers utilize this compound to explore its effects on cellular signaling cascades, such as the PI3K/Akt pathway, in various cell culture models.
Intended Use
- This product is sold strictly for in vitro laboratory research and development purposes ONLY.
- It is NOT intended for human or veterinary use, consumption, diagnostics, therapeutic applications, or any other use outside of controlled laboratory research.
- IGF-1 LR3, as supplied, is an experimental compound intended for scientific investigation into the mechanisms of the IGF-1 receptor signaling pathway in controlled laboratory settings.
- This product is NOT an FDA-approved drug, dietary supplement, or cosmetic or intended for any clinical use.
Handling and Storage
- Storage: Store lyophilized product at −20°C to −80°C. Protect from moisture and light. Store reconstituted product at 2°C to 8°C (standard refrigerator temperature).
- Reconstitution: Reconstitute with appropriate sterile laboratory solvents (e.g., sterile water, bacteriostatic water) immediately prior to research use, following established laboratory protocols for peptide handling.
- Safety: Handle using appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection, within a controlled laboratory environment.
Quality Assurance
- Our IGF-1 LR3 is synthesized to high purity specifications, verified by analytical methods such as HPLC and Mass Spectrometry.
- Purity and content is verified for every batch through third party testing.
Disclaimer
Purchase of this product signifies an agreement that it will be used solely for legitimate laboratory research purposes by qualified individuals trained in laboratory procedures and safety. The buyer assumes all responsibility for the proper handling, storage, use, and disposal of this product. The seller makes no claims regarding the suitability of this product for any particular research application beyond its specified chemical identity and purity. This product has not been evaluated by the Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease or condition. All product descriptions and details found on this website are intended for educational, research and informational purposes only.
COA Test Results
1 MG – IL3J0128 – Purity Endotoxin – 03/09/2026
0.1 MG (100 MCG) – IGL1113L – 01/29/2026
0.1 MG (100 MCG) – Endotoxin – IGL1113L – 01/29/2026
0.1 MG (100 MCG) – IG0809L – 09/03/2025












